Search on: LEUKEMIA INHIBITORY FACTOR 
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Descriptor English:   Leukemia Inhibitory Factor 
Descriptor Spanish:   Factor Inhibidor de Leucemia 
Descriptor Portuguese:   Fator Inibidor de Leucemia 
Synonyms English:   AM424
Cholinergic Differentiation Factor
D Factor (Leukemia Inhibitory Factor)
Differentiation-Stimulating Factor
Emfilermin
Myeloid Differentiation-Stimulating Factor
Differentiation Factor, Cholinergic
Differentiation Stimulating Factor
Differentiation-Stimulating Factor, Myeloid
Inhibitory Factor, Leukemia
Myeloid Differentiation Stimulating Factor  
Tree Number:   D12.644.276.374.470
D12.776.467.374.470
D23.529.374.470
Definition English:   An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor. 
History Note English:   2007(1980) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52282 
Unique Identifier:   D053605 

Occurrence in VHL: 		 

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